Sinofn Health
Sinofn Health
Vitamin A (including Retinol, Retinyl Palmitate, Retinyl Acetate, and Beta-Carotene) is a cornerstone of the global functional nutrition and pharmaceutical industries. Its role in maintaining vision integrity, promoting cell differentiation, modulating immune responses, and protecting epithelial tissue makes it indispensable. However, raw Vitamin A is notoriously vulnerable to environmental stressors: heat, UV radiation, oxygen exposure, and metallic trace minerals trigger rapid degradation, compromising potency and creating unwanted organoleptic alterations in functional foods and supplements.
As a leading national high-tech enterprise backed by the Chinese Academy of Sciences (CAS), SINOFN has resolved these stabilization challenges. We supply global brands with highly stabilized, custom micro-encapsulated Vitamin A powders, oil-in-water emulsions, and matrix-embedded beadlets. This ensures that the active compounds remain intact through complex distribution cycles and demanding shelf lives.
Conventional spray-dried Vitamin A powders suffer from high surface oil retention and micro-cracking, exposing the core molecule to light and oxygen. SINOFN employs a patented multi-layer matrix coating using natural gum polymers and nitrogen-purged spray-drying parameters. This limits surface oil to less than 0.5% and extends vitamin retention to over 95% under standard accelerated aging trials.
The demand for custom food-grade and medical-grade Vitamin A is growing due to rising rates of nutritional deficiency and the expansion of the clinical nutrition sector. SINOFN meets this demand with a 53,000㎡ advanced industrial complex, processing over 500 million product units annually. Our production guarantees consistent particle size, free-flow performance, and rapid cold-water dispersion, matching the workflow requirements of high-speed industrial tableting and encapsulation plants.
Vitamin A is fat-soluble and typically requires fat-rich digestion to be absorbed. SINOFN’s formulation team has developed self-emulsifying delivery systems (SEDS). These systems allow the hydrophobic vitamins to form uniform micelles when contact is made with gastric juices, increasing systemic absorption even on an empty stomach.
SINOFN Health Co., Ltd. is the dedicated contract manufacturing arm of the SINOFN Group. Founded in 2012 as a national high-tech enterprise, our core R&D pipeline is developed in strategic partnership with the Chinese Academy of Sciences (CAS). In 2025, we established our corporate and logistics hub in Shanghai to provide direct support to international brands, specialized clinical food markets, and dietary supplement distributors.
Our commitment to rigorous scientific research stems from our work in metabolic nutrition. Unlike typical supplement contract manufacturers focused only on basic mixing and tableting, SINOFN was built on clinical research. We develop targeted medical formulations (such as Foods for Special Medical Purposes or FSMP) and specialized nutritional solutions that demand strict chemical precision, clean-room environments, and complete trace allergen segregation.
Whether formulating Retinyl Palmitate for infant formulas or stabilizing high-potency Vitamin A for multivitamin gummies, we apply the same scientific rigor to every step of our process.
"We measure success not just in revenue, but in lives improved through accessible science."
During her clinical work, Mrs. Liu witnessed firsthand the lifelong challenges faced by children diagnosed with Phenylketonuria (PKU). Because specialized dietary products were financially out of reach for many families, she founded SINOFN in 2012 to develop affordable, science-backed PKU medical foods.
Her work attracted strategic venture investment and built our research foundation:
Through long-term academic partnerships with China's top biochemistry institutions, SINOFN has assembled an elite core of researchers to lead our formulation design and quality assurance operations.
Ph.D. from Peking University Medical School. Over 15 years of experience in metabolic disorder formulations and custom amino acid/vitamin complex design.
Associate Researcher and Postdoctoral Fellow at the Chinese Academy of Sciences (CAS). Specialist in bio-delivery systems, lipid micro-emulsions, and encapsulation stability.
Senior Scientist (Netherlands). Expert in European Food Safety Authority (EFSA) regulatory framework compliance and advanced nutraceutical delivery technologies.
Infant milk powders require Vitamin A ingredients with high dispersion, zero sediment, and clean organoleptic properties. We offer allergen-free, non-GMO Retinyl Palmitate micro-capsules. These are designed to survive thermal drying processes and dissolve rapidly in cold water.
Liquid formulations face challenges with separation and vitamin degradation from exposure to light. SINOFN provides stable nano-emulsions of Vitamin A. These keep liquid products clear, prevent sedimentation, and resist oxidation even in translucent packaging.
We produce highly flowable, dust-free dry beadlets with precise particle sizes. These beadlets blend uniformly with other minerals and amino acids in custom drink mixes, preventing segregation and clumping during packaging.
We transitioned our production line from basic spray-drying to multi-core encapsulation. This technology uses natural polysaccharides to shield unstable Retinol from oxidation, extending the shelf-life of finished products to 24 months.
We developed self-assembling micelle systems. These structures bypass the need for bile acid emulsification in the digestive tract, improving the absorption of fat-soluble vitamins.
To meet the growing demand for plant-based supplements, we introduced gelatin-free, starch-based Vitamin A beadlets. These are certified non-GMO, Halal, and Kosher, helping brands enter clean-label markets globally.
Different markets maintain distinct regulatory standards for Vitamin A dosages, chemical forms, and source materials. Navigating these requirements can be challenging for brands selling internationally. SINOFN provides full regulatory and compliance support to ensure your products meet local guidelines.
In the United States, we verify that our Vitamin A formulations comply with DSHEA (Dietary Supplement Health and Education Act) requirements and FDA labeling rules. For the European market, we adjust our formulations to meet EFSA (European Food Safety Authority) maximum daily intake levels and clean-label standards. This includes ensuring our products are free from allergens, plasticizers, and animal-derived starches.
Our raw material sourcing is fully traceable, and our facilities are regularly audited to comply with global food safety standards, including ISO 9001, ISO 22000, HACCP, and Halal certification.
Our manufacturing division provides comprehensive support for New Dietary Ingredient (NDI) notifications and dietary statement validations, helping streamline product registration in the US market.
Our facilities maintain strictly segregated production lines for allergen-sensitive and gelatin-free formulations. This ensures complete cross-contamination control for clean-label, vegan-certified products.
SINOFN holds 36 patents (including 11 invention patents, 12 utility models, 11 software copyrights, and 2 design patents) and 71 multi-category registered trademarks. Our facilities meet international quality and safety benchmarks.
